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Influence of binding affinity and blood plasma level on cerebral pharmacokinetics and PET imaging characteristics of two novel xanthine PET radioligands for the A1 adenosine receptor.
Schneider, Daniela; Oskamp, Angela; Holschbach, Marcus; Neumaier, Bernd; Bier, Dirk; Bauer, Andreas.
Affiliation
  • Schneider D; Institute of Neuroscience and Medicine - Molecular Organization of the Brain (INM-2), Forschungszentrum Jülich GmbH, 52428 Jülich, Germany. Electronic address: d.schneider@fz-juelich.de.
  • Oskamp A; Institute of Neuroscience and Medicine - Molecular Organization of the Brain (INM-2), Forschungszentrum Jülich GmbH, 52428 Jülich, Germany.
  • Holschbach M; Institute of Neuroscience and Medicine - Nuclear Chemistry (INM-5), Forschungszentrum Jülich GmbH, 52428 Jülich, Germany.
  • Neumaier B; Institute of Neuroscience and Medicine - Nuclear Chemistry (INM-5), Forschungszentrum Jülich GmbH, 52428 Jülich, Germany.
  • Bier D; Institute of Neuroscience and Medicine - Nuclear Chemistry (INM-5), Forschungszentrum Jülich GmbH, 52428 Jülich, Germany.
  • Bauer A; Institute of Neuroscience and Medicine - Molecular Organization of the Brain (INM-2), Forschungszentrum Jülich GmbH, 52428 Jülich, Germany; Neurological Department, Medical Faculty, Heinrich-Heine-University, Universitätsstraße 1, 40225 Düsseldorf, Germany.
Nucl Med Biol ; 82-83: 1-8, 2020.
Article in En | MEDLINE | ID: mdl-31838339
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Xanthine / Receptor, Adenosine A1 / Positron-Emission Tomography Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nucl Med Biol Journal subject: BIOLOGIA / MEDICINA NUCLEAR Year: 2020 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Xanthine / Receptor, Adenosine A1 / Positron-Emission Tomography Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nucl Med Biol Journal subject: BIOLOGIA / MEDICINA NUCLEAR Year: 2020 Document type: Article