Effect of atorvastatin on Aß<sub>1-42</sub> -induced alteration of SESN2, SIRT1, LC3II and TPP1 protein expressions in neuronal cell cultures.

Çelik, Hande; Karahan, Hande; Kelicen-Ugur, Pelin

Effect of atorvastatin on Aß_1-42 -induced alteration of SESN2, SIRT1, LC3II and TPP1 protein expressions in neuronal cell cultures.

Çelik, Hande; Karahan, Hande; Kelicen-Ugur, Pelin.

Affiliation

Çelik H; Faculty of Pharmacy, Department of Pharmacology, Hacettepe University, Ankara, Turkey.
Karahan H; Acibadem Molecular Pathology Laboratory, Istanbul, Turkey.
Kelicen-Ugur P; Stark Neurosciences Research Institute, Indiana University, Indianapolis, IN, USA.

J Pharm Pharmacol ; 72(3): 424-436, 2020 Mar.

Article in En | MEDLINE | ID: mdl-31846093

Subject(s)

Aminopeptidases/metabolism; Amyloid beta-Peptides/pharmacology; Atorvastatin/pharmacology; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/metabolism; Microtubule-Associated Proteins/metabolism; Nuclear Proteins/metabolism; Peptide Fragments/pharmacology; Serine Proteases/metabolism; Sirtuin 1/metabolism; Alzheimer Disease/metabolism; Apoptosis/drug effects; Autophagy/drug effects; Cell Line, Tumor; Cell Survival; Humans; Neuroblastoma; Neuroprotection/drug effects; Neuroprotective Agents/pharmacology; Tripeptidyl-Peptidase 1

Key words

Alzheimer's disease; atosvastatin; autophagy; sestrin-2; sirtuin-1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Nuclear Proteins / Amyloid beta-Peptides / Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / Sirtuin 1 / Serine Proteases / Atorvastatin / Aminopeptidases / Microtubule-Associated Proteins Type of study: Risk_factors_studies Limits: Humans Language: En Journal: J Pharm Pharmacol Year: 2020 Document type: Article Affiliation country: Turkey

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