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Glioblastoma cells vampirize WNT from neurons and trigger a JNK/MMP signaling loop that enhances glioblastoma progression and neurodegeneration.
Portela, Marta; Venkataramani, Varun; Fahey-Lozano, Natasha; Seco, Esther; Losada-Perez, Maria; Winkler, Frank; Casas-Tintó, Sergio.
Affiliation
  • Portela M; Instituto Cajal-CSIC, Madrid, Spain.
  • Venkataramani V; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.
  • Fahey-Lozano N; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Seco E; Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany.
  • Losada-Perez M; Instituto Cajal-CSIC, Madrid, Spain.
  • Winkler F; Instituto Cajal-CSIC, Madrid, Spain.
  • Casas-Tintó S; Instituto Cajal-CSIC, Madrid, Spain.
PLoS Biol ; 17(12): e3000545, 2019 12.
Article in En | MEDLINE | ID: mdl-31846454
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Glioblastoma / Matrix Metalloproteinases / MAP Kinase Signaling System / Wnt Signaling Pathway / Neurons Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: PLoS Biol Journal subject: BIOLOGIA Year: 2019 Document type: Article Affiliation country: Spain
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Glioblastoma / Matrix Metalloproteinases / MAP Kinase Signaling System / Wnt Signaling Pathway / Neurons Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: PLoS Biol Journal subject: BIOLOGIA Year: 2019 Document type: Article Affiliation country: Spain