Establishment and validation of an endoplasmic reticulum stress reporter to monitor zebrafish ATF6 activity in development and disease.

Clark, Eric M; Nonarath, Hannah J T; Bostrom, Jonathan R; Link, Brian A

Clark, Eric M; Nonarath, Hannah J T; Bostrom, Jonathan R; Link, Brian A.

Affiliation

Clark EM; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53214, USA.
Nonarath HJT; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53214, USA.
Bostrom JR; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53214, USA.
Link BA; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53214, USA blink@mcw.edu.

Dis Model Mech ; 13(1)2020 01 28.

Article in En | MEDLINE | ID: mdl-31852729

Subject(s)

Activating Transcription Factor 6/physiology; Endoplasmic Reticulum Stress; Zebrafish/embryology; Activating Transcription Factor 6/genetics; Amyotrophic Lateral Sclerosis/genetics; Animals; Disease Models, Animal; Neurodegenerative Diseases/genetics; Signal Transduction/physiology; Transgenes; Unfolded Protein Response

Key words

ATF6; Endoplasmic reticulum stress; Neurodegeneration; Unfolded protein response; Zebrafish

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Zebrafish / Activating Transcription Factor 6 / Endoplasmic Reticulum Stress Type of study: Prognostic_studies Limits: Animals Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom

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