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Carbamylation reduces the capacity of IgG for hexamerization and complement activation.
Lubbers, R; Oostindie, S C; Dijkstra, D J; Parren, P W H I; Verheul, M K; Abendstein, L; Sharp, T H; de Ru, A; Janssen, G M C; van Veelen, P A; van den Bremer, E T J; Bleijlevens, B; de Kreuk, B-J; Beurskens, F J; Trouw, L A.
Affiliation
  • Lubbers R; Department Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
  • Oostindie SC; Genmab, Utrecht, the Netherlands.
  • Dijkstra DJ; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
  • Parren PWHI; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
  • Verheul MK; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
  • Abendstein L; Lava Therapeutics, Utrecht, the Netherlands.
  • Sharp TH; Department Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
  • de Ru A; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Janssen GMC; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • van Veelen PA; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands.
  • van den Bremer ETJ; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands.
  • Bleijlevens B; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands.
  • de Kreuk BJ; Genmab, Utrecht, the Netherlands.
  • Beurskens FJ; Genmab, Utrecht, the Netherlands.
  • Trouw LA; Genmab, Utrecht, the Netherlands.
Clin Exp Immunol ; 200(1): 1-11, 2020 04.
Article in En | MEDLINE | ID: mdl-31853959
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Immunoglobulin G / Complement C1q / Complement Activation Limits: Aged / Humans / Male / Middle aged Language: En Journal: Clin Exp Immunol Year: 2020 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Immunoglobulin G / Complement C1q / Complement Activation Limits: Aged / Humans / Male / Middle aged Language: En Journal: Clin Exp Immunol Year: 2020 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom