Propacin, a coumarinolignoid isolated from durian, inhibits the lipopolysaccharide-induced inflammatory response in macrophages through the MAPK and NF-&#954;B pathways.

Huang, Yuying; Wang, Yihai; Xu, Jingwen; Feng, Jianying; He, Xiangjiu

Propacin, a coumarinolignoid isolated from durian, inhibits the lipopolysaccharide-induced inflammatory response in macrophages through the MAPK and NF-κB pathways.

Huang, Yuying; Wang, Yihai; Xu, Jingwen; Feng, Jianying; He, Xiangjiu.

Affiliation

Huang Y; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China. hexiangjiu@163.com shuiyuntian0101@126.com.

Food Funct ; 11(1): 596-605, 2020 Jan 29.

Article in En | MEDLINE | ID: mdl-31859327

Subject(s)

Anti-Inflammatory Agents/pharmacology; Bombacaceae/chemistry; Macrophages/drug effects; Macrophages/immunology; Mitogen-Activated Protein Kinases/immunology; NF-kappa B/immunology; Plant Extracts/pharmacology; Thiamphenicol/pharmacology; Animals; Cyclooxygenase 2/genetics; Cyclooxygenase 2/immunology; Lipopolysaccharides/adverse effects; Mice; Mitogen-Activated Protein Kinases/genetics; NF-kappa B/genetics; Nitric Oxide Synthase/genetics; Nitric Oxide Synthase/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiamphenicol / Plant Extracts / NF-kappa B / Mitogen-Activated Protein Kinases / Bombacaceae / Macrophages / Anti-Inflammatory Agents Limits: Animals Language: En Journal: Food Funct Year: 2020 Document type: Article Country of publication: United kingdom

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