Severity of white matter hyperintensities: Lesion patterns, cognition, and microstructural changes.

Zeng, Weiyi; Chen, Yaojing; Zhu, Zhibao; Gao, Shudan; Xia, Jianan; Chen, Xiaochun; Jia, Jianjun; Zhang, Zhanjun

Zeng, Weiyi; Chen, Yaojing; Zhu, Zhibao; Gao, Shudan; Xia, Jianan; Chen, Xiaochun; Jia, Jianjun; Zhang, Zhanjun.

Affiliation

Zeng W; Medical School of Chinese PLA, Beijing, China.
Chen Y; Department of Geriatric Neurology, The Second Medical Centre, Chinese PLA General Hospital, Beijing, China.
Zhu Z; State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Gao S; BABRI Centre, Beijing Normal University, Beijing, China.
Xia J; Department of Neurology, and Fujian Key Laboratory of Molecular Neurology, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Chen X; State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Jia J; BABRI Centre, Beijing Normal University, Beijing, China.
Zhang Z; State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.

J Cereb Blood Flow Metab ; 40(12): 2454-2463, 2020 12.

Article in En | MEDLINE | ID: mdl-31865841

Subject(s)

Brain/diagnostic imaging; Cognitive Dysfunction/pathology; Leukoaraiosis/diagnostic imaging; Magnetic Resonance Imaging/methods; White Matter/diagnostic imaging; Aged; Aging/pathology; Brain/pathology; Brain/ultrastructure; Case-Control Studies; Cognitive Dysfunction/diagnosis; Cognitive Dysfunction/physiopathology; Cross-Sectional Studies; Diffusion Tensor Imaging/methods; Female; Humans; Independent Living/statistics & numerical data; Leukoaraiosis/pathology; Male; Memory, Episodic; Memory, Short-Term/physiology; Middle Aged; Middle Cerebellar Peduncle/diagnostic imaging; Middle Cerebellar Peduncle/physiopathology; Neuropsychological Tests/standards; Severity of Illness Index; White Matter/abnormalities; White Matter/pathology; White Matter/ultrastructure

Key words

Cognitive impairment; diffusion tensor imaging; magnetic resonance imaging; non-demented elderly; white matter hyperintensities

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Magnetic Resonance Imaging / Leukoaraiosis / Cognitive Dysfunction / White Matter Type of study: Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: J Cereb Blood Flow Metab Year: 2020 Document type: Article Affiliation country: China

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