PKN1 controls the aggregation, spheroid formation, and viability of mouse embryonic fibroblasts in suspension culture.

Mehruba, Mona; Siddique, Salman Mahmud; Mukai, Hideyuki

Mehruba, Mona; Siddique, Salman Mahmud; Mukai, Hideyuki.

Affiliation

Mehruba M; Graduate School of Medicine, Kobe University, Kobe, 650-0017, Japan.
Siddique SM; Graduate School of Medicine, Kobe University, Kobe, 650-0017, Japan.
Mukai H; Graduate School of Medicine, Kobe University, Kobe, 650-0017, Japan; Biosignal Research Center, Kobe University, Kobe, 657-8501, Japan. Electronic address: mukinase@kobe-u.ac.jp.

Biochem Biophys Res Commun ; 523(2): 398-404, 2020 03 05.

Article in En | MEDLINE | ID: mdl-31870546

Subject(s)

Protein Kinase C/metabolism; Animals; Cadherins/metabolism; Cell Aggregation/physiology; Cell Membrane/metabolism; Cell Survival/physiology; Cells, Cultured; Fibroblasts/cytology; Fibroblasts/enzymology; Gene Knock-In Techniques; Integrin alpha5/metabolism; Integrin alphaV/metabolism; Mice; Mice, Mutant Strains; Point Mutation; Protein Kinase C/deficiency; Protein Kinase C/genetics; Spheroids, Cellular/cytology; Spheroids, Cellular/enzymology

Key words

Anoikis; Cadherin; Fibroblast; Integrin; Protein kinase; Spheroid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase C Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2020 Document type: Article Affiliation country: Japan Country of publication: United States

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