Spinal signalling of C-fiber mediated pleasant touch in humans.
Elife
; 82019 12 24.
Article
in En
| MEDLINE
| ID: mdl-31872799
ABSTRACT
C-tactile afferents form a distinct channel that encodes pleasant tactile stimulation. Prevailing views indicate they project, as with other unmyelinated afferents, in lamina I-spinothalamic pathways. However, we found that spinothalamic ablation in humans, whilst profoundly impairing pain, temperature and itch, had no effect on pleasant touch perception. Only discriminative touch deficits were seen. These findings preclude privileged C-tactile-lamina I-spinothalamic projections and imply integrated hedonic and discriminative spinal processing from the body.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pleasure-Pain Principle
/
Touch
/
Touch Perception
/
Pleasure
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Elife
Year:
2019
Document type:
Article
Affiliation country:
United kingdom