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Enzyme Evolution: An Epistatic Ratchet versus a Smooth Reversible Transition.
Ben-David, Moshe; Soskine, Misha; Dubovetskyi, Artem; Cherukuri, Kesava-Phaneendra; Dym, Orly; Sussman, Joel L; Liao, Qinghua; Szeler, Klaudia; Kamerlin, Shina Caroline Lynn; Tawfik, Dan S.
Affiliation
  • Ben-David M; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
  • Soskine M; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
  • Dubovetskyi A; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
  • Cherukuri KP; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
  • Dym O; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
  • Sussman JL; Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Liao Q; Department of Chemistry - BMC, Uppsala University, Uppsala, Sweden.
  • Szeler K; Department of Chemistry - BMC, Uppsala University, Uppsala, Sweden.
  • Kamerlin SCL; Department of Chemistry - BMC, Uppsala University, Uppsala, Sweden.
  • Tawfik DS; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Mol Biol Evol ; 37(4): 1133-1147, 2020 04 01.
Article in En | MEDLINE | ID: mdl-31873734

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Directed Molecular Evolution / Aryldialkylphosphatase Limits: Humans Language: En Journal: Mol Biol Evol Journal subject: BIOLOGIA MOLECULAR Year: 2020 Document type: Article Affiliation country: Israel Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Directed Molecular Evolution / Aryldialkylphosphatase Limits: Humans Language: En Journal: Mol Biol Evol Journal subject: BIOLOGIA MOLECULAR Year: 2020 Document type: Article Affiliation country: Israel Country of publication: United States