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Design, synthesis and antineoplastic activity of novel 20(S)-acylthiourea derivatives of camptothecin.
Yang, Cheng-Jie; Li, Bin; Zhang, Zhi-Jun; Gao, Jian-Mei; Wang, Mei-Juan; Zhao, Xiao-Bo; Song, Zi-Long; Liu, Ying-Qian; Li, Hu; Chen, Yuyuan; Lee, Kuo-Hsiung; Morris-Natschke, Susan L; Xu, Chuanrui.
Affiliation
  • Yang CJ; School of Pharmacy, Lanzhou University, Lanzhou, 730000, PR China.
  • Li B; School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, PR China.
  • Zhang ZJ; School of Pharmacy, Lanzhou University, Lanzhou, 730000, PR China.
  • Gao JM; School of Pharmacy, Lanzhou University, Lanzhou, 730000, PR China.
  • Wang MJ; School of Pharmacy, Lanzhou University, Lanzhou, 730000, PR China.
  • Zhao XB; School of Pharmacy, Lanzhou University, Lanzhou, 730000, PR China.
  • Song ZL; School of Pharmacy, Lanzhou University, Lanzhou, 730000, PR China.
  • Liu YQ; School of Pharmacy, Lanzhou University, Lanzhou, 730000, PR China; College of Pharmaceutical Science, Zhejiang Chinese Medical University, 310000, PR China. Electronic address: yqliu@lzu.edu.cn.
  • Li H; School of Pharmacy, Lanzhou University, Lanzhou, 730000, PR China.
  • Chen Y; School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, PR China.
  • Lee KH; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 27599, USA.
  • Morris-Natschke SL; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 27599, USA.
  • Xu C; School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, PR China.
Eur J Med Chem ; 187: 111971, 2020 Feb 01.
Article in En | MEDLINE | ID: mdl-31881457
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urea / Camptothecin / Drug Design / Antineoplastic Agents Limits: Animals / Female / Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Country of publication: France
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urea / Camptothecin / Drug Design / Antineoplastic Agents Limits: Animals / Female / Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Country of publication: France