Advances in the Research on Anticardiolipin Antibody.
J Immunol Res
; 2019: 8380214, 2019.
Article
in En
| MEDLINE
| ID: mdl-31886311
ABSTRACT
Anticardiolipin antibody (ACA) is a kind of autoantibody and is one of the antiphospholipid antibodies (aPLs). Phospholipids with a negative charge on platelets and endothelial cell membranes are ACA target antigens. ACA is common in systemic lupus erythematosus and other autoimmune diseases and is closely associated with thrombosis, thrombocytopenia, and spontaneous abortion. In 1983, Harris established a method for detecting ACA, and research on the antibody has gained worldwide attention and has developed rapidly. For this review, we browsed articles that cover most of the ACA-related studies in the last 25 years and extracted influential ideas and conclusions in this field.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Research
/
Autoantigens
/
Autoimmune Diseases
/
Cardiolipins
/
Antibodies, Anticardiolipin
/
Disease Susceptibility
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
En
Journal:
J Immunol Res
Year:
2019
Document type:
Article
Affiliation country:
China
Publication country:
EG
/
EGIPTO
/
EGITO
/
EGYPT