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IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease.
Ma, Hsiao-Yen; Yamamoto, Gen; Xu, Jun; Liu, Xiao; Karin, Daniel; Kim, Ju Youn; Alexandrov, Ludmil B; Koyama, Yukinori; Nishio, Takahiro; Benner, Chris; Heinz, Sven; Rosenthal, Sara B; Liang, Shuang; Sun, Mengxi; Karin, Gabriel; Zhao, Peng; Brodt, Pnina; Mckillop, Iain H; Quehenberger, Oswald; Dennis, Ed; Saltiel, Alan; Tsukamoto, Hidekazu; Gao, Bin; Karin, Michael; Brenner, David A; Kisseleva, Tatiana.
Affiliation
  • Ma HY; Department of Medicine, University of California San Diego, La Jolla, CA, USA; Department of Surgery, University of California San Diego, La Jolla, CA, USA.
  • Yamamoto G; Department of Medicine, University of California San Diego, La Jolla, CA, USA; Department of Surgery, University of California San Diego, La Jolla, CA, USA.
  • Xu J; Department of Medicine, University of California San Diego, La Jolla, CA, USA; Department of Surgery, University of California San Diego, La Jolla, CA, USA.
  • Liu X; Department of Medicine, University of California San Diego, La Jolla, CA, USA; Department of Surgery, University of California San Diego, La Jolla, CA, USA.
  • Karin D; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Kim JY; Department of Pharmacology, University of California San Diego, La Jolla, CA, USA.
  • Alexandrov LB; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.
  • Koyama Y; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Nishio T; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Benner C; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Heinz S; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Rosenthal SB; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Liang S; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Sun M; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Karin G; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Zhao P; Department of Pharmacology, University of California San Diego, La Jolla, CA, USA.
  • Brodt P; Department of Medicine, McGill University and the McGill University Health Center, Montreal, QC, Canada.
  • Mckillop IH; Department of Biology, University of North Carolina at Charlotte, Charlotte, NC, USA.
  • Quehenberger O; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Dennis E; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Saltiel A; Department of Pharmacology, University of California San Diego, La Jolla, CA, USA.
  • Tsukamoto H; Southern California Research Center for ALPD and Cirrhosis, Department of Pathology, Keck School of Medicine of USC, Los Angeles, CA, USA; Department of Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, USA.
  • Gao B; Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • Karin M; Department of Pharmacology, University of California San Diego, La Jolla, CA, USA.
  • Brenner DA; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Kisseleva T; Department of Surgery, University of California San Diego, La Jolla, CA, USA. Electronic address: tkisseleva@ucsd.edu.
J Hepatol ; 72(5): 946-959, 2020 05.
Article in En | MEDLINE | ID: mdl-31899206
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Carcinoma, Hepatocellular / Interleukin-17 / Hepatocytes / Kupffer Cells / Liver Cirrhosis / Liver Diseases, Alcoholic / Liver Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2020 Document type: Article Affiliation country: United States Country of publication: Netherlands
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Carcinoma, Hepatocellular / Interleukin-17 / Hepatocytes / Kupffer Cells / Liver Cirrhosis / Liver Diseases, Alcoholic / Liver Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2020 Document type: Article Affiliation country: United States Country of publication: Netherlands