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Multiregion exome sequencing of ovarian immature teratomas reveals 2N near-diploid genomes, paucity of somatic mutations, and extensive allelic imbalances shared across mature, immature, and disseminated components.
Heskett, Michael B; Sanborn, John Z; Boniface, Christopher; Goode, Benjamin; Chapman, Jocelyn; Garg, Karuna; Rabban, Joseph T; Zaloudek, Charles; Benz, Stephen C; Spellman, Paul T; Solomon, David A; Cho, Raymond J.
Affiliation
  • Heskett MB; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA.
  • Sanborn JZ; NantOmics, LLC, Culver City, CA, USA.
  • Boniface C; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA.
  • Goode B; Department of Pathology, University of California, San Francisco, CA, USA.
  • Chapman J; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA, USA.
  • Garg K; Department of Pathology, University of California, San Francisco, CA, USA.
  • Rabban JT; Department of Pathology, University of California, San Francisco, CA, USA.
  • Zaloudek C; Department of Pathology, University of California, San Francisco, CA, USA.
  • Benz SC; NantOmics, LLC, Culver City, CA, USA.
  • Spellman PT; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA.
  • Solomon DA; Department of Pathology, University of California, San Francisco, CA, USA. david.solomon@ucsf.edu.
  • Cho RJ; Department of Dermatology, University of California, San Francisco, CA, USA. raymond.cho@ucsf.edu.
Mod Pathol ; 33(6): 1193-1206, 2020 06.
Article in En | MEDLINE | ID: mdl-31911616
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Teratoma / Allelic Imbalance / Mutation Limits: Adolescent / Adult / Child / Female / Humans Language: En Journal: Mod Pathol Journal subject: PATOLOGIA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Teratoma / Allelic Imbalance / Mutation Limits: Adolescent / Adult / Child / Female / Humans Language: En Journal: Mod Pathol Journal subject: PATOLOGIA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States