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Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and restoring synaptic impairment in an amyloid precursor protein/presenilin 1 transgenic mouse model of Alzheimer's disease.
Zhu, Qing; Zhang, Nianping; Hu, Nan; Jiang, Rongrong; Lu, Huicong; Xuan, Aiguo; Long, Dahong; Chen, Yan.
Affiliation
  • Zhu Q; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510260, P.R. China.
  • Zhang N; The Teaching and Research Section of Surgery, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250355, P.R. China.
  • Hu N; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510260, P.R. China.
  • Jiang R; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510260, P.R. China.
  • Lu H; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510260, P.R. China.
  • Xuan A; Department of Human Anatomy, Guangzhou Medical University, Guangzhou, Guangdong 511436, P.R. China.
  • Long D; Department of Human Anatomy, Guangzhou Medical University, Guangzhou, Guangdong 511436, P.R. China.
  • Chen Y; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510260, P.R. China.
Mol Med Rep ; 21(3): 1172-1180, 2020 03.
Article in En | MEDLINE | ID: mdl-31922229

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Stem Cell Transplantation / Presenilin-1 / Neural Stem Cells / Cholinergic Neurons / Alzheimer Disease / Learning / Memory Limits: Animals Language: En Journal: Mol Med Rep Year: 2020 Document type: Article Country of publication: Greece

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Stem Cell Transplantation / Presenilin-1 / Neural Stem Cells / Cholinergic Neurons / Alzheimer Disease / Learning / Memory Limits: Animals Language: En Journal: Mol Med Rep Year: 2020 Document type: Article Country of publication: Greece