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The Effect of the Phospholipid Bilayer Environment on Cholesterol Crystal Polymorphism.
Varsano, Neta; Beghi, Fabio; Dadosh, Tali; Elad, Nadav; Pereiro, Eva; Haran, Gilad; Leiserowitz, Leslie; Addadi, Lia.
Affiliation
  • Varsano N; Department of Structural Biology, Weizmann Institute of Science, 234 Herzl Street, Rehovot, 76100, Israel.
  • Beghi F; Department of Chemistry, Università Degli Studi di Milano, 20122, Milano, Italy.
  • Dadosh T; Department of Chemical Research Support, Weizmann Institute of Science, Rehovot, 76100, Israel.
  • Elad N; Department of Chemical Research Support, Weizmann Institute of Science, Rehovot, 76100, Israel.
  • Pereiro E; MISTRAL Beamline-Experiments Division, ALBA Synchrotron Light Source, Cerdanyola del Valles, 08290, Barcelona, Spain.
  • Haran G; Department of Chemical & Biological Physics, Weizmann Institute of Science, Rehovot, 76100, Israel.
  • Leiserowitz L; Department of Materials and Interfaces, Weizmann Institute of Science, Rehovot, 76100, Israel.
  • Addadi L; Department of Structural Biology, Weizmann Institute of Science, 234 Herzl Street, Rehovot, 76100, Israel.
Chempluschem ; 84(4): 317, 2019 04.
Article in En | MEDLINE | ID: mdl-31939223
ABSTRACT
Invited for this month's cover are the group of Prof. Lia Addadi at the Weizmann Institute of Science, Israel and collaborators at the Università Degli Studi di Milano, Italy, and the ALBA Synchrotron Light Source, Spain. The front cover shows how cholesterol crystals form in macrophage cells and in lipid bilayers of different compositions. Cholesterol monohydrate stable triclinic crystals form in vitro as rhomb-shaped plates, whereas the monoclinic crystals fold into tubular or helical shapes. Read the full text of the article at 10.1002/cplu.201800632.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phospholipids / Cholesterol / Lipid Bilayers Limits: Humans Language: En Journal: Chempluschem Year: 2019 Document type: Article Affiliation country: Israel

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phospholipids / Cholesterol / Lipid Bilayers Limits: Humans Language: En Journal: Chempluschem Year: 2019 Document type: Article Affiliation country: Israel