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iPSC-Based Modeling of RAG2 Severe Combined Immunodeficiency Reveals Multiple T Cell Developmental Arrests.
Themeli, Maria; Chhatta, Amiet; Boersma, Hester; Prins, Henk Jan; Cordes, Martijn; de Wilt, Edwin; Farahani, Aïda Shahrabi; Vandekerckhove, Bart; van der Burg, Mirjam; Hoeben, Rob C; Staal, Frank J T; Mikkers, Harald M M.
Affiliation
  • Themeli M; Department of Hematology, Amsterdam UMC, Location VUmc, Cancer Center Amsterdam, Amsterdam 1081 HV, The Netherlands.
  • Chhatta A; Department of Immunohematology & Blood Transfusion, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.
  • Boersma H; Department of Cell & Chemical Biology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • Prins HJ; Department of Hematology, Amsterdam UMC, Location VUmc, Cancer Center Amsterdam, Amsterdam 1081 HV, The Netherlands.
  • Cordes M; Department of Immunohematology & Blood Transfusion, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.
  • de Wilt E; Department of Clinical Genetics, Leiden University Medical Center, Leiden 2333 ZC, The Netherlands.
  • Farahani AS; Department of Hematology, Amsterdam UMC, Location VUmc, Cancer Center Amsterdam, Amsterdam 1081 HV, The Netherlands.
  • Vandekerckhove B; Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Gent 9000, Belgium.
  • van der Burg M; Department of Immunology, Erasmus Medical Center, Rotterdam 3015 GE, The Netherlands.
  • Hoeben RC; Department of Cell & Chemical Biology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • Staal FJT; Department of Immunohematology & Blood Transfusion, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.
  • Mikkers HMM; Department of Cell & Chemical Biology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands; LUMC hiPSC Hotel, Leiden University Medical Center, Leiden 2333 ZC, The Netherlands. Electronic address: h.mikkers@lumc.nl.
Stem Cell Reports ; 14(2): 300-311, 2020 02 11.
Article in En | MEDLINE | ID: mdl-31956083
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Severe Combined Immunodeficiency / DNA-Binding Proteins / Induced Pluripotent Stem Cells / Models, Biological Limits: Animals / Humans Language: En Journal: Stem Cell Reports Year: 2020 Document type: Article Affiliation country: Netherlands Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Severe Combined Immunodeficiency / DNA-Binding Proteins / Induced Pluripotent Stem Cells / Models, Biological Limits: Animals / Humans Language: En Journal: Stem Cell Reports Year: 2020 Document type: Article Affiliation country: Netherlands Country of publication: United States