PARP inhibitors: a tsunami of indications in different malignancies.

Haddad, Gaëlle; Saadé, Marie Christelle; Eid, Roland; Haddad, Fady Gh; Kourie, Hampig Raphael

Haddad, Gaëlle; Saadé, Marie Christelle; Eid, Roland; Haddad, Fady Gh; Kourie, Hampig Raphael.

Affiliation

Haddad G; Hematology & Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
Saadé MC; Hematology & Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
Eid R; Hematology & Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
Haddad FG; Hematology & Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
Kourie HR; Hematology & Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.

Pharmacogenomics ; 21(3): 221-230, 2020 02.

Article in En | MEDLINE | ID: mdl-31967513

Subject(s)

Neoplasms/drug therapy; Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use; Precision Medicine/methods; BRCA1 Protein/genetics; BRCA2 Protein/genetics; Clinical Trials as Topic; DNA Repair/drug effects; Drug Approval; Humans; Mutation; Neoplasms/genetics; Neoplasms/metabolism; Neoplasms/mortality; Poly(ADP-ribose) Polymerase Inhibitors/administration & dosage; Poly(ADP-ribose) Polymerase Inhibitors/pharmacokinetics; Survival Analysis

Key words

breast; PARP inhibitors; cancer; ovarian

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precision Medicine / Poly(ADP-ribose) Polymerase Inhibitors / Neoplasms Limits: Humans Language: En Journal: Pharmacogenomics Journal subject: FARMACOLOGIA / GENETICA MEDICA Year: 2020 Document type: Article Affiliation country: Lebanon Country of publication: United kingdom

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