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Arginine π-stacking drives binding to fibrils of the Alzheimer protein Tau.
Ferrari, Luca; Stucchi, Riccardo; Konstantoulea, Katerina; van de Kamp, Gerarda; Kos, Renate; Geerts, Willie J C; van Bezouwen, Laura S; Förster, Friedrich G; Altelaar, Maarten; Hoogenraad, Casper C; Rüdiger, Stefan G D.
Affiliation
  • Ferrari L; Cellular Protein Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
  • Stucchi R; Science for Life, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
  • Konstantoulea K; Science for Life, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
  • van de Kamp G; Cell Biology, Neurobiology and Biophysics, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
  • Kos R; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
  • Geerts WJC; Cellular Protein Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
  • van Bezouwen LS; Science for Life, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
  • Förster FG; Cellular Protein Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
  • Altelaar M; Science for Life, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
  • Hoogenraad CC; Cellular Protein Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
  • Rüdiger SGD; Science for Life, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
Nat Commun ; 11(1): 571, 2020 Jan 29.
Article in En | MEDLINE | ID: mdl-31996674

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arginine / Protein Binding / Tau Proteins / Alzheimer Disease / Amyloid Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arginine / Protein Binding / Tau Proteins / Alzheimer Disease / Amyloid Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom