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Selective metabotropic glutamate receptor 2 positive allosteric modulation alleviates L-DOPA-induced psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset.
Sid-Otmane, Lamia; Hamadjida, Adjia; Nuara, Stephen G; Bédard, Dominique; Gaudette, Fleur; Gourdon, Jim C; Michaud, Véronique; Beaudry, Francis; Panisset, Michel; Huot, Philippe.
Affiliation
  • Sid-Otmane L; Département de Pharmacologie et Physiologie, Université de Montréal, Montreal, QC, Canada.
  • Hamadjida A; Neurodegenerative Disease Group, Montreal Neurological Institute, Montreal, QC, Canada.
  • Nuara SG; Comparative Medicine & Animal Resource Centre, McGill University, Montreal, QC, Canada.
  • Bédard D; Neurodegenerative Disease Group, Montreal Neurological Institute, Montreal, QC, Canada.
  • Gaudette F; Plateforme de Pharmacocinétique, Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
  • Gourdon JC; Comparative Medicine & Animal Resource Centre, McGill University, Montreal, QC, Canada.
  • Michaud V; Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Lake Nona Campus, Orlando, FL, USA.
  • Beaudry F; Groupe de Recherche en Pharmacologie Animale du Québec, Département de Biomédecine Vétérinaire, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada.
  • Panisset M; Unité des troubles du mouvement André-Barbeau, Service de Neurologie, Département de Médecine, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada; Département de Neurosciences, Université de Montréal, Montreal, QC, Canada.
  • Huot P; Département de Pharmacologie et Physiologie, Université de Montréal, Montreal, QC, Canada; Neurodegenerative Disease Group, Montreal Neurological Institute, Montreal, QC, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada; Movement Disorder Clinic, Division of
Eur J Pharmacol ; 873: 172957, 2020 Apr 15.
Article in En | MEDLINE | ID: mdl-32004527
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psychoses, Substance-Induced / Pyridines / Sulfonamides / Antipsychotic Agents / Behavior, Animal / Levodopa / Receptors, Metabotropic Glutamate / GABA Modulators / MPTP Poisoning / Dyskinesia, Drug-Induced Type of study: Prognostic_studies Aspects: Patient_preference Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2020 Document type: Article Affiliation country: Canada Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psychoses, Substance-Induced / Pyridines / Sulfonamides / Antipsychotic Agents / Behavior, Animal / Levodopa / Receptors, Metabotropic Glutamate / GABA Modulators / MPTP Poisoning / Dyskinesia, Drug-Induced Type of study: Prognostic_studies Aspects: Patient_preference Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2020 Document type: Article Affiliation country: Canada Country of publication: Netherlands