APOE-amyloid interaction: Therapeutic targets.

Wisniewski, Thomas; Drummond, Eleanor

Wisniewski, Thomas; Drummond, Eleanor.

Affiliation

Wisniewski T; Departments of Neurology, Pathology and Psychiatry, Center for Cognitive Neurology, NYU School of Medicine, Science Building, Rm 1017, 435 East 30(th) Street, New York, NY 10016, USA. Electronic address: Thomas.wisniewski@nyulangone.org.
Drummond E; Brain & Mind Centre and Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.

Neurobiol Dis ; 138: 104784, 2020 05.

Article in En | MEDLINE | ID: mdl-32027932

Subject(s)

Apolipoproteins E/metabolism; Plaque, Amyloid/metabolism; Alleles; Alzheimer Disease/metabolism; Alzheimer Disease/therapy; Amyloid beta-Peptides/antagonists & inhibitors; Amyloid beta-Peptides/metabolism; Animals; Apolipoprotein E4/antagonists & inhibitors; Apolipoprotein E4/metabolism; Apolipoproteins E/antagonists & inhibitors; Brain/metabolism; Drug Delivery Systems; Humans; Mice

Key words

Apolipoprotein E; Beta amyloid; Early onset AD; Immunomodulation; Interaction; Oligomers; Pathological chaperone; Peptoids; Therapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Plaque, Amyloid Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2020 Document type: Article Country of publication: United States

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