Detoxifying effects of optimal hyperoxia (40% oxygenation) exposure on benzo[a]pyrene-induced toxicity in human keratinocytes.

Chan Kwon, Yong; Sik Kim, Hyung; Lee, Byung-Mu

Chan Kwon, Yong; Sik Kim, Hyung; Lee, Byung-Mu.

Affiliation

Chan Kwon Y; Division of Toxicology, College of Pharmacy, Sungkyunkwan University, Suwon, South Korea.
Sik Kim H; Division of Toxicology, College of Pharmacy, Sungkyunkwan University, Suwon, South Korea.
Lee BM; Division of Toxicology, College of Pharmacy, Sungkyunkwan University, Suwon, South Korea.

J Toxicol Environ Health A ; 83(2): 82-94, 2020 01 17.

Article in En | MEDLINE | ID: mdl-32065759

Subject(s)

Benzo(a)pyrene/toxicity; Keratinocytes/drug effects; Keratinocytes/metabolism; Oxygen/pharmacology; Aging/physiology; Cell Line; Cell Survival; DNA Damage; Free Radicals; Gene Expression Regulation, Enzymologic/drug effects; Humans; Hydrogen-Ion Concentration; Skin/metabolism; Superoxide Dismutase

Key words

Nrf2; Optimal hyperoxia; antioxidant; benzo[a]pyrene; detoxification; oxygen

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxygen / Benzo(a)pyrene / Keratinocytes Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Toxicol Environ Health A Journal subject: SAUDE AMBIENTAL / TOXICOLOGIA Year: 2020 Document type: Article Affiliation country: South Korea Country of publication: United kingdom

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