A suggested bisphenol A metabolite (MBP) interfered with reproductive organ development in the chicken embryo while a human-relevant mixture of phthalate monoesters had no such effects.

Mentor, Anna; Bornehag, Carl-Gustaf; Jönsson, Maria; Mattsson, Anna

Mentor, Anna; Bornehag, Carl-Gustaf; Jönsson, Maria; Mattsson, Anna.

Affiliation

Mentor A; Department of Environmental Toxicology, Uppsala University, Uppsala, Sweden.
Bornehag CG; Department of Environmental Medicine and Public Health, Centre for Reproductive Biology in Uppsala (CRU), Uppsala, Sweden.
Jönsson M; Public Health Sciences, Karlstad University, Karlstad, Sweden.
Mattsson A; Icahn School of Medicine at Mount Sinai, New York, NY, USA.

J Toxicol Environ Health A ; 83(2): 66-81, 2020 01 17.

Article in En | MEDLINE | ID: mdl-32077375

Subject(s)

Benzhydryl Compounds/metabolism; Benzhydryl Compounds/toxicity; Phenols/metabolism; Phenols/toxicity; Phthalic Acids/chemistry; Sex Determination Processes/drug effects; Animals; Benzhydryl Compounds/chemistry; Chick Embryo; Female; Gene Expression Regulation, Developmental/drug effects; Humans; Male; Mullerian Ducts/drug effects; Mullerian Ducts/embryology; Ovary/drug effects; Ovary/embryology; Phenols/chemistry; Phthalic Acids/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Testis/drug effects; Testis/embryology

Key words

4-bis(4-hydroxyphenyl)pent-1-ene (MBP); 4-methyl-2; Chicken embryo; feminization; mixture; phthalates

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenols / Phthalic Acids / Benzhydryl Compounds / Sex Determination Processes Limits: Animals / Female / Humans / Male Language: En Journal: J Toxicol Environ Health A Journal subject: SAUDE AMBIENTAL / TOXICOLOGIA Year: 2020 Document type: Article Affiliation country: Sweden

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google