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Prolonging gavage feeds for reduction of gastroesophageal reflux in infants.
Favara, Michael T; Abraham, Sheeja; DiPalma, Joan; Epstein, Michele; Greenspan, Jay S; Aghai, Zubair H.
Affiliation
  • Favara MT; Neonatology/Christiana Care Health System, Newark, DE, 19713, USA.
  • Abraham S; Pediatric Gastroenterology/Thomas Jefferson University/Nemours, Philadelphia, PA, 19107, USA.
  • DiPalma J; Pediatric Gastroenterology/Thomas Jefferson University/Nemours, Philadelphia, PA, 19107, USA.
  • Epstein M; Pediatric Gastroenterology/Thomas Jefferson University/Nemours, Philadelphia, PA, 19107, USA.
  • Greenspan JS; Neonatology/Thomas Jefferson University/Nemours, Philadelphia, PA, 19107, USA.
  • Aghai ZH; Neonatology/Thomas Jefferson University/Nemours, Philadelphia, PA, 19107, USA. zaghai@nemours.org.
J Perinatol ; 40(6): 916-921, 2020 06.
Article in En | MEDLINE | ID: mdl-32086438
OBJECTIVE: To determine if prolonging gavage feedings in infants for ≥60 min is associated with decreased gastroesophageal reflux (GER) compared with bolus feeding using multiple-channel intraluminal impedance with pH probe (MII-pH). STUDY DESIGN: Retrospective analysis of infants who underwent MII-pH between October 2009 and July 2018 and received gavage feedings. Infants were divided into two groups: bolus (<30 min) or prolonged (≥60 min). Symptoms, number of reflux events and percent time pH < 4 was compared. RESULT: Fifty-eight infants underwent evaluation. Thirty-one (54%) received bolus gavage feedings and 27 (46%) received prolonged feedings. Groups differed in postmenstrual age. Total reflux episodes were significantly lower with prolonged feeding (median 19 vs. 28 episodes, p = 0.015), with no difference in acid exposure time. There was no significant difference in GER symptoms between the two groups. CONCLUSION: Prolongation of gavage feedings was associated with decreased total numbers of GER events without reduction in GER symptoms.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gastroesophageal Reflux Type of study: Observational_studies / Risk_factors_studies Limits: Humans / Infant Language: En Journal: J Perinatol Journal subject: PERINATOLOGIA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gastroesophageal Reflux Type of study: Observational_studies / Risk_factors_studies Limits: Humans / Infant Language: En Journal: J Perinatol Journal subject: PERINATOLOGIA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States