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Oxidative stress-mediated genotoxicity of malathion in human lymphocytes.
Olakkaran, Shilpa; Kizhakke Purayil, Anupama; Antony, Anet; Mallikarjunaiah, Shanthala; Hunasanahally Puttaswamygowda, Gurushankara.
Affiliation
  • Olakkaran S; Department of Zoology, School of Biological Sciences, Central University of Kerala, Tejaswini Hills, Periya, 671 320, Kasaragod, India.
  • Kizhakke Purayil A; Department of Zoology, School of Biological Sciences, Central University of Kerala, Tejaswini Hills, Periya, 671 320, Kasaragod, India.
  • Antony A; Department of Zoology, School of Biological Sciences, Central University of Kerala, Tejaswini Hills, Periya, 671 320, Kasaragod, India.
  • Mallikarjunaiah S; Center for Applied Genetics, Department of Studies in Zoology, Bangalore University, Jnanabharathi, Bengaluru, 560056, Karnataka, India.
  • Hunasanahally Puttaswamygowda G; Department of Zoology, School of Biological Sciences, Central University of Kerala, Tejaswini Hills, Periya, 671 320, Kasaragod, India. Electronic address: hpgurushankara@gmail.com.
Mutat Res Genet Toxicol Environ Mutagen ; 849: 503138, 2020 Jan.
Article in En | MEDLINE | ID: mdl-32087854
ABSTRACT
Applying the single-cell gel electrophoresis (comet) assay, we show that the widely used organophosphorus pesticide malathion is cytotoxic, genotoxic, and induces oxidative stress in human lymphocytes.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocytes / Oxidants / Cytotoxins / Insecticides / Malathion / Mutagens Limits: Adult / Female / Humans / Male Language: En Journal: Mutat Res Genet Toxicol Environ Mutagen Year: 2020 Document type: Article Affiliation country: India
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocytes / Oxidants / Cytotoxins / Insecticides / Malathion / Mutagens Limits: Adult / Female / Humans / Male Language: En Journal: Mutat Res Genet Toxicol Environ Mutagen Year: 2020 Document type: Article Affiliation country: India