Inhibition of DDR1 reduces invasive features of human A375 melanoma, HT29 colon carcinoma and SK-HEP hepatoma cells.

Romayor, Irene; Badiola, Iker; Olaso, Elvira

Romayor, Irene; Badiola, Iker; Olaso, Elvira.

Affiliation

Romayor I; Department of Cell Biology and Histology, School of Medicine and Dentistry, University of the Basque Country, Leioa, Spain.
Badiola I; Department of Cell Biology and Histology, School of Medicine and Dentistry, University of the Basque Country, Leioa, Spain.
Olaso E; Department of Cell Biology and Histology, School of Medicine and Dentistry, University of the Basque Country, Leioa, Spain.

Cell Adh Migr ; 14(1): 69-81, 2020 12.

Article in En | MEDLINE | ID: mdl-32090682

Subject(s)

Carcinoma, Hepatocellular/pathology; Colonic Neoplasms/pathology; Discoidin Domain Receptor 1/antagonists & inhibitors; Liver Neoplasms/pathology; Melanoma/pathology; Biomarkers, Tumor/metabolism; Carcinoma, Hepatocellular/metabolism; Cell Adhesion; Cell Adhesion Molecules/metabolism; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemotaxis; Collagen Type I/metabolism; Colonic Neoplasms/metabolism; Discoidin Domain Receptor 1/genetics; Discoidin Domain Receptor 1/metabolism; Gene Silencing; Humans; Liver Neoplasms/metabolism; MAP Kinase Signaling System; Matrix Metalloproteinase 9/metabolism; Melanoma/metabolism; Neoplasm Invasiveness; Phosphorylation; Proto-Oncogene Proteins c-akt/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Small Interfering/metabolism

Key words

Melanoma; adhesion; collagen receptor; colon carcinoma; discoidin domain receptor 1; hepatocarcinoma; invasion; matrix metalloproteinases; migration; proliferation; silencing

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colonic Neoplasms / Carcinoma, Hepatocellular / Discoidin Domain Receptor 1 / Liver Neoplasms / Melanoma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Adh Migr Year: 2020 Document type: Article Affiliation country: Spain Country of publication: United States

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