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C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.
Wang, Mingmei; Wang, Hongfeng; Tao, Zhouteng; Xia, Qin; Hao, Zongbing; Prehn, Jochen H M; Zhen, Xuechu; Wang, Guanghui; Ying, Zheng.
Affiliation
  • Wang M; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
  • Wang H; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
  • Tao Z; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
  • Xia Q; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
  • Hao Z; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
  • Prehn JHM; Department of Physiology & Medical Physics and FUTURE-NEURO Research Centre, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Zhen X; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
  • Wang G; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
  • Ying Z; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Aging Cell ; 19(4): e13126, 2020 04.
Article in En | MEDLINE | ID: mdl-32100453
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Monomeric GTP-Binding Proteins / Mechanistic Target of Rapamycin Complex 1 / C9orf72 Protein / Lysosomes Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Aging Cell Year: 2020 Document type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Monomeric GTP-Binding Proteins / Mechanistic Target of Rapamycin Complex 1 / C9orf72 Protein / Lysosomes Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Aging Cell Year: 2020 Document type: Article Affiliation country: China