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Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
Xie, Yiyue; Tummala, Padmaja; Oakley, Aaron J; Deora, Girdhar Singh; Nakano, Yuji; Rooke, Melissa; Cuellar, Matthew E; Strasser, Jessica M; Dahlin, Jayme L; Walters, Michael A; Casarotto, Marco G; Board, Philip G; Baell, Jonathan B.
Affiliation
  • Xie Y; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
  • Tummala P; John Curtin School of Medical Research, Australian National University, Canberra, ACT 2600, Australia.
  • Oakley AJ; Molecular Horizons and School of Chemistry and Molecular Bioscience and Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia.
  • Deora GS; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
  • Nakano Y; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
  • Rooke M; John Curtin School of Medical Research, Australian National University, Canberra, ACT 2600, Australia.
  • Cuellar ME; Institute for Therapeutics Discovery and Development, University of Minnesota, 717 Delaware Street SE, Minneapolis, Minnesota 55414, United States.
  • Strasser JM; Institute for Therapeutics Discovery and Development, University of Minnesota, 717 Delaware Street SE, Minneapolis, Minnesota 55414, United States.
  • Dahlin JL; Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, Massachusetts 02115, United States.
  • Walters MA; Institute for Therapeutics Discovery and Development, University of Minnesota, 717 Delaware Street SE, Minneapolis, Minnesota 55414, United States.
  • Casarotto MG; John Curtin School of Medical Research, Australian National University, Canberra, ACT 2600, Australia.
  • Board PG; John Curtin School of Medical Research, Australian National University, Canberra, ACT 2600, Australia.
  • Baell JB; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, People's Republic of China.
J Med Chem ; 63(6): 2894-2914, 2020 03 26.
Article in En | MEDLINE | ID: mdl-32105470
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Enzyme Inhibitors / Glutathione Transferase Limits: Animals / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2020 Document type: Article Affiliation country: Australia Country of publication: United States
Fulltext
Add to My VHL
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Enzyme Inhibitors / Glutathione Transferase Limits: Animals / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2020 Document type: Article Affiliation country: Australia Country of publication: United States