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Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials.
Hong, David S; DuBois, Steven G; Kummar, Shivaani; Farago, Anna F; Albert, Catherine M; Rohrberg, Kristoffer S; van Tilburg, Cornelis M; Nagasubramanian, Ramamoorthy; Berlin, Jordan D; Federman, Noah; Mascarenhas, Leo; Geoerger, Birgit; Dowlati, Afshin; Pappo, Alberto S; Bielack, Stefan; Doz, François; McDermott, Ray; Patel, Jyoti D; Schilder, Russell J; Tahara, Makoto; Pfister, Stefan M; Witt, Olaf; Ladanyi, Marc; Rudzinski, Erin R; Nanda, Shivani; Childs, Barrett H; Laetsch, Theodore W; Hyman, David M; Drilon, Alexander.
Affiliation
  • Hong DS; University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • DuBois SG; Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Harvard Medical School, Boston, MA, USA.
  • Kummar S; Stanford University School of Medicine, Stanford University, Palo Alto, CA, USA.
  • Farago AF; Massachusetts General Hospital, Boston, MA, USA.
  • Albert CM; Seattle Children's Hospital, University of Washington, Seattle, WA, USA.
  • Rohrberg KS; Rigshospitalet, Copenhagen University, Copenhagen, Denmark.
  • van Tilburg CM; Hopp Children's Cancer Center Heidelberg, Heidelberg University Hospital, Heidelberg, Germany; German Cancer Research Center, Heidelberg, Germany.
  • Nagasubramanian R; Nemours Children's Hospital, Orlando, FL, USA.
  • Berlin JD; Vanderbilt University Medical Center, Nashville, TN, USA.
  • Federman N; David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
  • Mascarenhas L; Saban Research Institute, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Geoerger B; Gustave Roussy Cancer Center, Department of Pediatric and Adolescent Oncology, Université Paris-Saclay, Villejuif, France.
  • Dowlati A; University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
  • Pappo AS; St Jude Children's Research Hospital, Memphis, TN, USA.
  • Bielack S; Klinikum Stuttgart-Olgahospital, Stuttgart Cancer Center, Pediatrics 5 (Oncology, Hematology, Immunology), Stuttgart, Germany.
  • Doz F; SIREDO Center Care, Innovation, Research In Pediatric, Adolescent and Young Adult Oncology, Institut Curie and Paris Descartes University, Paris, France.
  • McDermott R; St Vincent's University Hospital and Cancer Trials Ireland, Dublin, Ireland.
  • Patel JD; University of Chicago, Chicago, IL, USA.
  • Schilder RJ; Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.
  • Tahara M; National Cancer Center Hospital East, Kashiwa, Japan.
  • Pfister SM; Hopp Children's Cancer Center Heidelberg, Heidelberg University Hospital, Heidelberg, Germany; German Cancer Research Center, Heidelberg, Germany; German Cancer Network, Heidelberg, Germany.
  • Witt O; Hopp Children's Cancer Center Heidelberg, Heidelberg University Hospital, Heidelberg, Germany; German Cancer Research Center, Heidelberg, Germany.
  • Ladanyi M; Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Rudzinski ER; Seattle Children's Hospital, Seattle, WA, USA.
  • Nanda S; Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA.
  • Childs BH; Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA.
  • Laetsch TW; University of Texas Southwestern Medical Center/Children's Health, Dallas, TX, USA.
  • Hyman DM; Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical College, New York, NY, USA.
  • Drilon A; Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical College, New York, NY, USA. Electronic address: drilona@mskcc.org.
Lancet Oncol ; 21(4): 531-540, 2020 04.
Article in En | MEDLINE | ID: mdl-32105622
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyrimidines / Proteins / Neoplasms Limits: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male Language: En Journal: Lancet Oncol Journal subject: NEOPLASIAS Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyrimidines / Proteins / Neoplasms Limits: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male Language: En Journal: Lancet Oncol Journal subject: NEOPLASIAS Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom