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Chronic wasting disease (CWD) prion strains evolve via adaptive diversification of conformers in hosts expressing prion protein polymorphisms.
Duque Velásquez, Camilo; Kim, Chae; Haldiman, Tracy; Kim, Chiye; Herbst, Allen; Aiken, Judd; Safar, Jiri G; McKenzie, Debbie.
Affiliation
  • Duque Velásquez C; Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2R3, Canada.
  • Kim C; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta T6G 2M8, Canada.
  • Haldiman T; Department of Pathology, Case Western Reserve University, Cleveland, Ohio 44106.
  • Kim C; Department of Pathology, Case Western Reserve University, Cleveland, Ohio 44106.
  • Herbst A; Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2R3, Canada.
  • Aiken J; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta T6G 2M8, Canada.
  • Safar JG; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta T6G 2M8, Canada.
  • McKenzie D; Department of Agricultural, Food and Nutritional Sciences, University of Alberta, Edmonton, Alberta T6G 2P5, Canada.
J Biol Chem ; 295(15): 4985-5001, 2020 04 10.
Article in En | MEDLINE | ID: mdl-32111742

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Brain / PrPC Proteins / Wasting Disease, Chronic / Host Adaptation Limits: Animals Language: En Journal: J Biol Chem Year: 2020 Document type: Article Affiliation country: Canada Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Brain / PrPC Proteins / Wasting Disease, Chronic / Host Adaptation Limits: Animals Language: En Journal: J Biol Chem Year: 2020 Document type: Article Affiliation country: Canada Country of publication: United States