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Population Pharmacokinetics and Pharmacodynamics of Ontamalimab (SHP647), a Fully Human Monoclonal Antibody Against Mucosal Addressin Cell Adhesion Molecule-1 (MAdCAM-1), in Patients With Ulcerative Colitis or Crohn's Disease.
Wang, Yi; Marier, Jean-Francois; Lavigne, Jean; Kassir, Nastya; Martin, Patrick.
Affiliation
  • Wang Y; Shire, a Takeda company, Cambridge, Massachusetts, USA.
  • Marier JF; Certara Strategic Consulting, Princeton, New Jersey, USA.
  • Lavigne J; Certara Strategic Consulting, Princeton, New Jersey, USA.
  • Kassir N; Certara Strategic Consulting, Princeton, New Jersey, USA.
  • Martin P; Shire, a Takeda company, Cambridge, Massachusetts, USA.
J Clin Pharmacol ; 60(7): 903-914, 2020 07.
Article in En | MEDLINE | ID: mdl-32119128
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gastrointestinal Agents / Colitis, Ulcerative / Crohn Disease / Cell Adhesion Molecules / Antibodies, Monoclonal, Humanized / Mucoproteins Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Clin Pharmacol Year: 2020 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gastrointestinal Agents / Colitis, Ulcerative / Crohn Disease / Cell Adhesion Molecules / Antibodies, Monoclonal, Humanized / Mucoproteins Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Clin Pharmacol Year: 2020 Document type: Article Affiliation country: United States