Defining Stage-Specific Activity of Potent New Inhibitors of Cryptosporidium parvum Growth <i>In Vitro</i>.

Funkhouser-Jones, Lisa J; Ravindran, Soumya; Sibley, L David

Defining Stage-Specific Activity of Potent New Inhibitors of Cryptosporidium parvum Growth In Vitro.

Funkhouser-Jones, Lisa J; Ravindran, Soumya; Sibley, L David.

Affiliation

Funkhouser-Jones LJ; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Ravindran S; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Sibley LD; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA sibley@wustl.edu.

mBio ; 11(2)2020 03 03.

Article in En | MEDLINE | ID: mdl-32127445

Subject(s)

Antiprotozoal Agents/pharmacology; Cryptosporidium parvum/drug effects; Cryptosporidium parvum/growth & development; Enzyme Inhibitors/pharmacology; Epithelial Cells/drug effects; Life Cycle Stages/drug effects; 1-Phosphatidylinositol 4-Kinase/antagonists & inhibitors; Antiprotozoal Agents/classification; Cell Line; Cell Line, Tumor; Enzyme Inhibitors/classification; Epithelial Cells/parasitology; Humans

Key words

cryptosporidiosis; enteric pathogen; intestinal stem cells; mechanism of action; primary cell culture; small-molecule inhibitors; target identification

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cryptosporidium parvum / Enzyme Inhibitors / Epithelial Cells / Life Cycle Stages / Antiprotozoal Agents Type of study: Guideline / Prognostic_studies Limits: Humans Language: En Journal: MBio Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google