Significance of lncRNA MIR31HG in predicting the prognosis for Chinese patients with cancer: a meta-analysis.
Biomark Med
; 14(4): 303-316, 2020 03.
Article
in En
| MEDLINE
| ID: mdl-32134327
ABSTRACT
It is important to clarify the significance of long noncoding RNA MIR31 host gene (lncRNA MIR31HG) in predicting the prognosis for malignant tumors through meta-analysis. Electronic databases were systemically searched, from inception until 2 January 2019, to identify related articles. Meanwhile, the hazard ratios (odds ratios) and 95% CIs were computed for exploring the association between the expression of lncRNA MIR31HG and the survival (pathological variables). Eleven studies with 1041 cases were enrolled into the current meta-analysis. Low expression of lncRNA MIR31HG showed correlation with the dismal overall survival, disease-free survival, high tumor stage and lymph node metastasis among patients with digestive system cancers. Low expression of lncRNA MIR31HG may serve as a potential novel factor to indicate the dismal prognosis and metastasis in patients with digestive system cancers.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Asian People
/
RNA, Long Noncoding
/
Neoplasms
Type of study:
Prognostic_studies
/
Risk_factors_studies
/
Systematic_reviews
Limits:
Humans
Language:
En
Journal:
Biomark Med
Journal subject:
BIOQUIMICA
/
MEDICINA
Year:
2020
Document type:
Article
Affiliation country:
China