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Structural basis for pharmacological modulation of the TRPC6 channel.
Bai, Yonghong; Yu, Xinchao; Chen, Hao; Horne, Daniel; White, Ryan; Wu, Xiaosu; Lee, Paul; Gu, Yan; Ghimire-Rijal, Sudipa; Lin, Daniel C-H; Huang, Xin.
Affiliation
  • Bai Y; Department of Molecular Engineering, Amgen Research, Amgen Inc, Cambridge, United States.
  • Yu X; Department of Molecular Engineering, Amgen Research, Amgen Inc, South San Francisco, United States.
  • Chen H; Department of Protein Technologies, Amgen Research, Amgen Inc, Cambridge, United States.
  • Horne D; Department of Medicinal Chemistry, Amgen Research, Amgen Inc, Cambridge, United States.
  • White R; Department of Medicinal Chemistry, Amgen Research, Amgen Inc, Cambridge, United States.
  • Wu X; Department of Cardiometabolic Disorders, Amgen Research, Amgen Inc, South San Francisco, United States.
  • Lee P; Department of Discovery Technologies, Amgen Research, Amgen Inc, South San Francisco, United States.
  • Gu Y; Department of Protein Technologies, Amgen Research, Amgen Inc, Cambridge, United States.
  • Ghimire-Rijal S; Department of Molecular Engineering, Amgen Research, Amgen Inc, Cambridge, United States.
  • Lin DC; Department of Cardiometabolic Disorders, Amgen Research, Amgen Inc, South San Francisco, United States.
  • Huang X; Department of Molecular Engineering, Amgen Research, Amgen Inc, Cambridge, United States.
Elife ; 92020 03 09.
Article in En | MEDLINE | ID: mdl-32149605
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium Channel Blockers / Diglycerides / TRPC6 Cation Channel Limits: Humans Language: En Journal: Elife Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium Channel Blockers / Diglycerides / TRPC6 Cation Channel Limits: Humans Language: En Journal: Elife Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom