[A Case of Synchronous Bilateral Neuroendocrine Ductal Carcinoma In Situ].
Gan To Kagaku Ryoho
; 46(13): 2222-2224, 2019 Dec.
Article
in Ja
| MEDLINE
| ID: mdl-32156885
ABSTRACT
Neuroendocrine ductal carcinoma in situ(NE-DCIS)is a unique subtype of ductal carcinoma in situ(DCIS)that is not described in the general rules for clinical and pathological recording of breast cancer. NE-DCIS is described as an unusual variant of DCIS in the 2012 World Health Organization(WHO)classification. The chief complaint in NE-DCIS is hemorrhagic nipple discharge. The histological characteristics of NE-DCIS are solid growth of cancer cells with granular and spindle-shaped nuclei. Histologically, NE-DCIS is suggestive of low malignancy but a poor prognosis of neuroendocrine carcinoma of the breast has been reported. The report by Honami et al was the only other report of synchronous bilateral neuroendocrine ductal carcinoma in situ. We report the second case of NE-DCIS diagnosed synchronously in both breasts in a patient who had visited our outpatient clinic with hemorrhagic nipple discharge.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Breast Neoplasms
/
Carcinoma in Situ
/
Carcinoma, Neuroendocrine
/
Carcinoma, Intraductal, Noninfiltrating
Type of study:
Prognostic_studies
Limits:
Humans
Language:
Ja
Journal:
Gan To Kagaku Ryoho
Year:
2019
Document type:
Article