[A Case of Histological Complete Remission after Chemotherapy for Paraaortic Lymph Node Recurrence after Colon Cancer Surgery].

ABSTRACT

In September 2013, a 50-year-old woman presented to our hospital with right abdominal pain as the main complaint. Careful examinations led to the diagnosis of ascending colon cancer. In October 2013, resection of the right half colon and removal of the D3 lymph nodes were performed. As postoperative adjunctive chemotherapy, 6 courses of CAPOX therapy were initiated. PET-CT conducted 17 months after the surgery revealed an enlarged right para-aoric lymph nodes and abnormal FDG accumulation. Lymph node recurrence was diagnosed. In April 2015, 10 courses of CAPOX plus BEV therapy, followed by 12courses of capecitabine single agent, were initiated. PET-CT revealed complete remission of the right para-aoric lymph nodes. However, abnormal FDG accumulation was detected in the right ovary and uterine corpus. After careful examinations in March 2017, we performed expanded total hysterectomy, bilateral resection of the appendicular organs, resection of body reticular region, and removal of the lymph nodes and those at the right side of the aorta for the ovarian and uterine cancer. Pathologically, intimal cancer in the right ovary and uterine corpus was diagnosed. Examination of the right para-aoric lymph nodes resected at the same time showed complete remission on images, although histological complete remission was found with scarring. Currently, 63 months after the initial surgery, the patient is alive without recurrence.