Long-term metal exposure changes gut microbiota of residents surrounding a mining and smelting area.
Sci Rep
; 10(1): 4453, 2020 03 10.
Article
in En
| MEDLINE
| ID: mdl-32157109
ABSTRACT
In this epidemiologic study, 16 S rRNA sequencing was used to investigate the changes of diversity and composition profile of gut microbiota resulting from long-term exposure to multiple metals, including arsenic (As), cadmium (Cd), cuprum (Cu), lead (Pb), and zinc (Zn). Due to long-term exposure to various metals, the relative abundances of Lachnospiraceae, Eubacterium eligens, Ruminococcaceae UGG-014, Erysipelotrichaceae UCG-003, Tyzzerella 3, Bacteroides, Slackia, italics, and Roseburia were found to become much higher, whereas the abundance of Prevotella 9 presented an opposite trend. Additionally, differences between males and female groups were found, such as the greater richness and evenness of bacteria for men subjected to long-term metal exposure in polluted areas. The changes of men's microbiomes were more significant as a result of higher daily intake, mining and smelting activity, and living habits. This research presents a new theoretical basis for the correlation between long-term metal exposure and gut health for people living in contaminated areas.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Soil Pollutants
/
Bacteria
/
Metals, Heavy
/
Environmental Exposure
/
Gastrointestinal Microbiome
/
Mining
Type of study:
Etiology_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Sci Rep
Year:
2020
Document type:
Article
Affiliation country:
China