A transient &#945;-helix in the N-terminal RNA recognition motif of polypyrimidine tract binding protein senses RNA secondary structure.

Maris, Christophe; Jayne, Sandrine; Damberger, Fred F; Beusch, Irene; Dorn, Georg; Ravindranathan, Sapna; Allain, Frédéric H-T

A transient α-helix in the N-terminal RNA recognition motif of polypyrimidine tract binding protein senses RNA secondary structure.

Maris, Christophe; Jayne, Sandrine; Damberger, Fred F; Beusch, Irene; Dorn, Georg; Ravindranathan, Sapna; Allain, Frédéric H-T.

Affiliation

Maris C; Department of Biology, ETH Zurich, 8093 Zürich, Switzerland.
Jayne S; Department of Biology, ETH Zurich, 8093 Zürich, Switzerland.
Damberger FF; Department of Biology, ETH Zurich, 8093 Zürich, Switzerland.
Beusch I; Department of Biology, ETH Zurich, 8093 Zürich, Switzerland.
Dorn G; Department of Biology, ETH Zurich, 8093 Zürich, Switzerland.
Ravindranathan S; Central NMR facility, National Chemical Laboratory, Pune 411008 India.
Allain FH; Department of Biology, ETH Zurich, 8093 Zürich, Switzerland.

Nucleic Acids Res ; 48(8): 4521-4537, 2020 05 07.

Article in En | MEDLINE | ID: mdl-32170319

Subject(s)

Polypyrimidine Tract-Binding Protein/chemistry; RNA Recognition Motif; RNA/chemistry; Encephalomyocarditis virus/genetics; Internal Ribosome Entry Sites; Models, Molecular; Mutation; Nucleic Acid Conformation; Polypyrimidine Tract-Binding Protein/genetics; Polypyrimidine Tract-Binding Protein/metabolism; Protein Binding; Protein Conformation, alpha-Helical; RNA/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA / Polypyrimidine Tract-Binding Protein / RNA Recognition Motif Type of study: Prognostic_studies Language: En Journal: Nucleic Acids Res Year: 2020 Document type: Article Affiliation country: Switzerland Country of publication: United kingdom

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