Sex- and gender-associated clinical and psychosocial characteristics of patients with psoriasis.
Clin Exp Dermatol
; 45(6): 705-711, 2020 Aug.
Article
in En
| MEDLINE
| ID: mdl-32170752
ABSTRACT
BACKGROUND:
Sex and gender may affect disease prevalence, adverse effects and response to therapy.AIM:
To analyse sex and gender differences in outpatients with psoriasis.METHODS:
A cross-sectional study was conducted at IDI-IRCCS, Rome, over a 3-year period. In total, 3023 patients with psoriasis were enrolled. Anthropometric and demographic characteristics were recorded, and a dermatologist evaluated the clinical severity of disease. Quality of life (QoL) questionnaires were collected. Univariate and multivariate analyses were performed to examine factors associated with sex.RESULTS:
We found sex- and gender-associated differences in clinical characteristics, disease severity, psychological distress and quality of life. Male sex was associated with body mass index, smoking, alcohol consumption, Psoriasis Area Severity Index ≥ 10 and age at onset ≥ 20 years. Female sex was associated with family history of diabetes, joint involvement, clinical type other than diffuse plaque psoriasis, higher psychological distress and a greater effect on QoL.CONCLUSION:
Our study identified sex and gender differences of potential clinical relevance in psoriasis.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Psoriasis
/
Sex Factors
/
Sex Characteristics
Type of study:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspects:
Determinantes_sociais_saude
/
Patient_preference
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Clin Exp Dermatol
Year:
2020
Document type:
Article
Affiliation country:
Italy