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Nitrosative Stress and Lipid Homeostasis as a Mechanism for Zileuton Hepatotoxicity and Resistance in Genetically Sensitive Mice.
You, Dahea; Lyn-Cook, Lascelles E; Gatti, Daniel M; Bell, Natalie; Mayeux, Philip R; James, Laura P; Mattes, William B; Larson, Gary J; Harrill, Alison H.
Affiliation
  • You D; Division of the National Toxicology Program, The National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709.
  • Lyn-Cook LE; Graduate Program in Interdisciplinary Biomedical Sciences, The University of Arkansas for Medical Sciences and Arkansas Children's Research Institute, Little Rock, Arkansas 72205.
  • Gatti DM; The Jackson Laboratory, Bar Harbor, Maine 04609.
  • Bell N; Division of the National Toxicology Program, The National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709.
  • Mayeux PR; East Carolina University, Greenville, North Carolina 27858.
  • James LP; Department of Pharmacology and Toxicology.
  • Mattes WB; Department of Pediatrics, The University of Arkansas for Medical Sciences and Arkansas Children's Research Institute, Little Rock, Arkansas 27705.
  • Larson GJ; Division of Systems Biology, The National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arkansas 72079.
  • Harrill AH; Social & Scientific Systems, Inc., Durham, North Carolina 27703.
Toxicol Sci ; 175(2): 220-235, 2020 06 01.
Article in En | MEDLINE | ID: mdl-32170957
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Genetic Predisposition to Disease / Chemical and Drug Induced Liver Injury / Nitrosative Stress / Homeostasis / Hydroxyurea / Lipids Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2020 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Genetic Predisposition to Disease / Chemical and Drug Induced Liver Injury / Nitrosative Stress / Homeostasis / Hydroxyurea / Lipids Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2020 Document type: Article Country of publication: United States