Dietary quality index is negatively associated with serum advanced glycation end products in healthy adults.

BACKGROUND AND AIMS: In human, advanced glycation end products (AGEs) can endogenously formed or exogenously ingested from foods and tobacco. Dietary quality is an important factor to prevent many disorders. This study sought to determine any association between AGEs and diet quality. METHODS: The participants were 90 healthy adults, aged higher than 20 years. Dietary intake of individuals was collected using two 24-h dietary recalls and quality of diets were determined by dietary quality index-International (DQI-I). Serum levels of pentosidine and carboxymethyl-lysine (CML) were examined by ELISA. RESULTS: Total DQI-I score was 62.3 ± 1.3. Variety, adequacy, moderation, and the overall balance of diet scores in the study participants were 16.5 ± 0.4, 25.8 ± 0.5, 17.7 ± 0.9, and 2.4 ± 0.3, respectively. Participants with higher age (>40 years), higher education level, moderate calorie intake and married had significantly greater DQI-I score. Diet quality was positively associated with participants' education level (r = 0.28, p = 0.008). DQI-I score negatively correlated with serum levels of CML and pentosidine (r = -0.42, P < 0.001 and r = -0.35, P < 0.001, respectively). CONCLUSION: Dietary modification may be beneficial for controlling AGE accumulation in the body and subsequently in reduction of chronic diseases risk.