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Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia.
Hysi, Pirro G; Choquet, Hélène; Khawaja, Anthony P; Wojciechowski, Robert; Tedja, Milly S; Yin, Jie; Simcoe, Mark J; Patasova, Karina; Mahroo, Omar A; Thai, Khanh K; Cumberland, Phillippa M; Melles, Ronald B; Verhoeven, Virginie J M; Vitart, Veronique; Segre, Ayellet; Stone, Richard A; Wareham, Nick; Hewitt, Alex W; Mackey, David A; Klaver, Caroline C W; MacGregor, Stuart; Khaw, Peng T; Foster, Paul J; Guggenheim, Jeremy A; Rahi, Jugnoo S; Jorgenson, Eric; Hammond, Christopher J.
Affiliation
  • Hysi PG; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK. pirro.hysi@kcl.ac.uk.
  • Choquet H; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK. pirro.hysi@kcl.ac.uk.
  • Khawaja AP; UCL Great Ormond Street Institute of Child Health, University College London, London, UK. pirro.hysi@kcl.ac.uk.
  • Wojciechowski R; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
  • Tedja MS; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
  • Yin J; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK.
  • Simcoe MJ; Department of Biophysics, Johns Hopkins University, Baltimore, MD, USA.
  • Patasova K; Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Mahroo OA; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Thai KK; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Cumberland PM; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
  • Melles RB; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Verhoeven VJM; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK.
  • Vitart V; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK.
  • Segre A; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
  • Stone RA; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
  • Wareham N; UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Hewitt AW; Ulverscroft Vision Research Group, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Mackey DA; Department of Ophthalmology Kaiser Permanente Northern California, Redwood City, CA, USA.
  • Klaver CCW; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.
  • MacGregor S; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Khaw PT; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Foster PJ; Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear, Boston, MA, USA.
  • Guggenheim JA; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK.
  • Rahi JS; Department of Ophthalmology, Royal Hobart Hospital, Hobart, Tasmania, Australia.
  • Jorgenson E; Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Western Australia, Australia.
  • Hammond CJ; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.
Nat Genet ; 52(4): 401-407, 2020 04.
Article in En | MEDLINE | ID: mdl-32231278
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Refractive Errors / Genetic Predisposition to Disease / Myopia Type of study: Prognostic_studies / Systematic_reviews Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2020 Document type: Article Affiliation country: United kingdom Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Refractive Errors / Genetic Predisposition to Disease / Myopia Type of study: Prognostic_studies / Systematic_reviews Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2020 Document type: Article Affiliation country: United kingdom Country of publication: United States