One-stop radiotherapeutic targeting of primary and distant osteosarcoma to inhibit cancer progression and metastasis using 2DG-grafted graphene quantum dots.

Tung, Fu-I; Zheng, Lu-Jun; Hou, Kai-Ting; Chiang, Chih-Sheng; Chen, Ming-Hong; Liu, Tse-Ying

Tung, Fu-I; Zheng, Lu-Jun; Hou, Kai-Ting; Chiang, Chih-Sheng; Chen, Ming-Hong; Liu, Tse-Ying.

Affiliation

Tung FI; Department of Orthopaedic Surgery, Taipei City Hospital, Yangming branch, Taipei City 112, Taiwan. fui.tung@gmail.com.

Nanoscale ; 12(16): 8809-8818, 2020 Apr 30.

Article in En | MEDLINE | ID: mdl-32250377

Subject(s)

Deoxyglucose/chemistry; Graphite/chemistry; Osteosarcoma/radiotherapy; Quantum Dots/therapeutic use; Radiation-Sensitizing Agents/chemistry; Animals; Cell Line, Tumor; Cell Movement/drug effects; Cell Survival/drug effects; DNA Damage; Deoxyglucose/pharmacokinetics; Deoxyglucose/therapeutic use; Drug Delivery Systems; Glucose/chemistry; Glucose/pharmacokinetics; Glucose/therapeutic use; Graphite/pharmacokinetics; Graphite/therapeutic use; Humans; Mice; Neoplasm Metastasis/prevention & control; Osteosarcoma/metabolism; Osteosarcoma/pathology; Quantum Dots/chemistry; Radiation-Sensitizing Agents/pharmacokinetics; Radiation-Sensitizing Agents/therapeutic use; Reactive Oxygen Species/metabolism; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation-Sensitizing Agents / Osteosarcoma / Quantum Dots / Deoxyglucose / Graphite Limits: Animals / Humans Language: En Journal: Nanoscale Year: 2020 Document type: Article Affiliation country: Taiwan Country of publication: United kingdom

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