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Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions.
Thompson, Oliver; von Meyenn, Ferdinand; Hewitt, Zoe; Alexander, John; Wood, Andrew; Weightman, Richard; Gregory, Sian; Krueger, Felix; Andrews, Simon; Barbaric, Ivana; Gokhale, Paul J; Moore, Harry D; Reik, Wolf; Milo, Marta; Nik-Zainal, Serena; Yusa, Kosuke; Andrews, Peter W.
Affiliation
  • Thompson O; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • von Meyenn F; Epigenetics Programme, Babraham Institute, Cambridge, CB22 3AT, UK.
  • Hewitt Z; Department of Medical & Molecular Genetics, King's College London, London, SE1 9RT, UK.
  • Alexander J; Institute of Food, Nutrition and Health, ETH Zurich, 8603, Schwerzenbach, Switzerland.
  • Wood A; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • Weightman R; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • Gregory S; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
  • Krueger F; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • Andrews S; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • Barbaric I; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • Gokhale PJ; Bioinformatics Group, Babraham Institute, Cambridge, CB22 3AT, UK.
  • Moore HD; Bioinformatics Group, Babraham Institute, Cambridge, CB22 3AT, UK.
  • Reik W; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • Milo M; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • Nik-Zainal S; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • Yusa K; Epigenetics Programme, Babraham Institute, Cambridge, CB22 3AT, UK.
  • Andrews PW; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
Nat Commun ; 11(1): 1528, 2020 03 23.
Article in En | MEDLINE | ID: mdl-32251294
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Culture Techniques / DNA, Intergenic / Chromosomes, Human, X / Pluripotent Stem Cells / Mutation Rate Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Culture Techniques / DNA, Intergenic / Chromosomes, Human, X / Pluripotent Stem Cells / Mutation Rate Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: United kingdom