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The sialidase inhibitor 2,3-dehydro-2-deoxy-N-acetylneuraminic acid is a glucose-dependent potentiator of insulin secretion.
Minami, Akira; Fujita, Yuka; Shimba, Sumika; Shiratori, Mako; Kaneko, Yukiko K; Sawatani, Toshiaki; Otsubo, Tadamune; Ikeda, Kiyoshi; Kanazawa, Hiroaki; Mikami, Yasuyo; Sekita, Risa; Kurebayashi, Yuuki; Takahashi, Tadanobu; Miyagi, Taeko; Ishikawa, Tomohisa; Suzuki, Takashi.
Affiliation
  • Minami A; Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan. aminami@u-shizuoka-ken.ac.jp.
  • Fujita Y; Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
  • Shimba S; Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
  • Shiratori M; Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
  • Kaneko YK; Department of Pharmacology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
  • Sawatani T; Department of Pharmacology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
  • Otsubo T; Department of Organic Chemistry, School of Pharmaceutical Sciences, Hiroshima International University, Hiroshima, 737-0112, Japan.
  • Ikeda K; Department of Organic Chemistry, School of Pharmaceutical Sciences, Hiroshima International University, Hiroshima, 737-0112, Japan.
  • Kanazawa H; Department of Functional Anatomy, School of Nursing, University of Shizuoka, Shizuoka, 422-8526, Japan.
  • Mikami Y; Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
  • Sekita R; Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
  • Kurebayashi Y; Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
  • Takahashi T; Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
  • Miyagi T; Miyagi Cancer Center Research Institute, Natori, 981-1293, Japan.
  • Ishikawa T; Department of Pharmacology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
  • Suzuki T; Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan. suzukit@u-shizuoka-ken.ac.jp.
Sci Rep ; 10(1): 5198, 2020 03 23.
Article in En | MEDLINE | ID: mdl-32251344
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: N-Acetylneuraminic Acid / Insulin-Secreting Cells / Insulin Secretion / Glucose / Neuraminidase Limits: Animals Language: En Journal: Sci Rep Year: 2020 Document type: Article Affiliation country: Japan Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: N-Acetylneuraminic Acid / Insulin-Secreting Cells / Insulin Secretion / Glucose / Neuraminidase Limits: Animals Language: En Journal: Sci Rep Year: 2020 Document type: Article Affiliation country: Japan Country of publication: United kingdom