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Inhibition of protective immunity against Staphylococcus aureus infection by MHC-restricted immunodominance is overcome by vaccination.
Si, Youhui; Zhao, Fan; Beesetty, Pavani; Weiskopf, Daniela; Li, Zhaotao; Tian, Qiaomu; Alegre, Maria-Luisa; Sette, Alessandro; Chong, Anita S; Montgomery, Christopher P.
Affiliation
  • Si Y; Department of Surgery, University of Chicago, Chicago, IL, USA.
  • Zhao F; Department of Surgery, University of Chicago, Chicago, IL, USA.
  • Beesetty P; Center for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
  • Weiskopf D; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA.
  • Li Z; Center for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
  • Tian Q; Department of Surgery, University of Chicago, Chicago, IL, USA.
  • Alegre ML; Department of Medicine, University of Chicago, Chicago, IL, USA.
  • Sette A; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA.
  • Chong AS; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Montgomery CP; Department of Surgery, University of Chicago, Chicago, IL, USA.
Sci Adv ; 6(14): eaaw7713, 2020 04.
Article in En | MEDLINE | ID: mdl-32270029
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Staphylococcal Infections / Staphylococcus aureus / Immunodominant Epitopes / Host-Pathogen Interactions / Immune Tolerance / Major Histocompatibility Complex Type of study: Prognostic_studies Limits: Animals Language: En Journal: Sci Adv Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Staphylococcal Infections / Staphylococcus aureus / Immunodominant Epitopes / Host-Pathogen Interactions / Immune Tolerance / Major Histocompatibility Complex Type of study: Prognostic_studies Limits: Animals Language: En Journal: Sci Adv Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States