M2-Like Microglia Polarization Attenuates Neuropathic Pain Associated with Alzheimer's Disease.

Jin, Jing; Guo, Jia; Cai, Hongbin; Zhao, Chongchong; Wang, Huan; Liu, Zhiyan; Ge, Zhao-Ming

Jin, Jing; Guo, Jia; Cai, Hongbin; Zhao, Chongchong; Wang, Huan; Liu, Zhiyan; Ge, Zhao-Ming.

Affiliation

Jin J; Department of Neurology, the Second Hospital of Lanzhou University, Lanzhou, China.
Guo J; Department of Neurology, the Second Hospital of Lanzhou University, Lanzhou, China.
Cai H; Department of Neurology, the Second Hospital of Lanzhou University, Lanzhou, China.
Zhao C; Department of Neurology, the Second Hospital of Lanzhou University, Lanzhou, China.
Wang H; Department of Neurology, the Second Hospital of Lanzhou University, Lanzhou, China.
Liu Z; Department of Neurology, the Second Hospital of Lanzhou University, Lanzhou, China.
Ge ZM; Department of Neurology, the Second Hospital of Lanzhou University, Lanzhou, China.

J Alzheimers Dis ; 76(4): 1255-1265, 2020.

Article in En | MEDLINE | ID: mdl-32280102

Subject(s)

Alzheimer Disease/therapy; Cytokines/metabolism; Microglia/cytology; Neuralgia/therapy; Alzheimer Disease/complications; Alzheimer Disease/metabolism; Animals; Humans; Mice; Neuralgia/complications; Neuralgia/metabolism; Phenotype; Signal Transduction/physiology

Key words

Alzheimer's disease; microglia polarization; neuropathic pain; shDNMT1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytokines / Microglia / Alzheimer Disease / Neuralgia Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: J Alzheimers Dis Journal subject: GERIATRIA / NEUROLOGIA Year: 2020 Document type: Article Affiliation country: China Country of publication: Netherlands

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