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Industrial Approach to Determine the Relative Contribution of Seven Major UGT Isoforms to Hepatic Glucuronidation.
Busse, David; Leandersson, Sara; Amberntsson, Sara; Darnell, Malin; Hilgendorf, Constanze.
Affiliation
  • Busse D; Clinical Pharmacology & Quantitative Pharmacology, Clinical Pharmacology and Safety Science, R&D, AstraZeneca Gothenburg, Sweden.
  • Leandersson S; Clinical Pharmacology & Quantitative Pharmacology, Clinical Pharmacology and Safety Science, R&D, AstraZeneca Gothenburg, Sweden.
  • Amberntsson S; Functional and Mechanistic Safety Hepatic Safety, Clinical Pharmacology and Safety Science, R&D, AstraZeneca Gothenburg, Sweden.
  • Darnell M; Clinical Pharmacology & Quantitative Pharmacology, Clinical Pharmacology and Safety Science, R&D, AstraZeneca Gothenburg, Sweden.
  • Hilgendorf C; DMPK, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca Gothenburg, Sweden. Electronic address: Constanze.Hilgendorf@astrazeneca.com.
J Pharm Sci ; 109(7): 2309-2320, 2020 07.
Article in En | MEDLINE | ID: mdl-32294459
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glucuronosyltransferase / Glucuronides Limits: Humans Language: En Journal: J Pharm Sci Year: 2020 Document type: Article Affiliation country: Sweden Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glucuronosyltransferase / Glucuronides Limits: Humans Language: En Journal: J Pharm Sci Year: 2020 Document type: Article Affiliation country: Sweden Country of publication: United States