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LRP1 is a master regulator of tau uptake and spread.
Rauch, Jennifer N; Luna, Gabriel; Guzman, Elmer; Audouard, Morgane; Challis, Collin; Sibih, Youssef E; Leshuk, Carolina; Hernandez, Israel; Wegmann, Susanne; Hyman, Bradley T; Gradinaru, Viviana; Kampmann, Martin; Kosik, Kenneth S.
Affiliation
  • Rauch JN; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA.
  • Luna G; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA.
  • Guzman E; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA.
  • Audouard M; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA.
  • Challis C; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
  • Sibih YE; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA.
  • Leshuk C; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA.
  • Hernandez I; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA.
  • Wegmann S; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.
  • Hyman BT; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Gradinaru V; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
  • Kampmann M; Institute for Neurodegenerative Diseases, Department of Biochemistry and Biophysics, The California Institute for Quantitative Biomedical Research, Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.
  • Kosik KS; Chan Zuckerberg Biohub, San Francisco, CA, USA.
Nature ; 580(7803): 381-385, 2020 04.
Article in En | MEDLINE | ID: mdl-32296178
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Low Density Lipoprotein Receptor-Related Protein-1 Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nature Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Low Density Lipoprotein Receptor-Related Protein-1 Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nature Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom