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FS222, a CD137/PD-L1 Tetravalent Bispecific Antibody, Exhibits Low Toxicity and Antitumor Activity in Colorectal Cancer Models.
Lakins, Matthew A; Koers, Alexander; Giambalvo, Raffaella; Munoz-Olaya, Jose; Hughes, Robert; Goodman, Emma; Marshall, Sylwia; Wollerton, Francisca; Batey, Sarah; Gliddon, Daniel; Tuna, Mihriban; Brewis, Neil.
Affiliation
  • Lakins MA; F-star Therapeutics Ltd., Cambridge, United Kingdom. matthew.lakins@f-star.com.
  • Koers A; F-star Therapeutics Ltd., Cambridge, United Kingdom.
  • Giambalvo R; F-star Therapeutics Ltd., Cambridge, United Kingdom.
  • Munoz-Olaya J; F-star Therapeutics Ltd., Cambridge, United Kingdom.
  • Hughes R; F-star Therapeutics Ltd., Cambridge, United Kingdom.
  • Goodman E; F-star Therapeutics Ltd., Cambridge, United Kingdom.
  • Marshall S; F-star Therapeutics Ltd., Cambridge, United Kingdom.
  • Wollerton F; F-star Therapeutics Ltd., Cambridge, United Kingdom.
  • Batey S; F-star Therapeutics Ltd., Cambridge, United Kingdom.
  • Gliddon D; F-star Therapeutics Ltd., Cambridge, United Kingdom.
  • Tuna M; F-star Therapeutics Ltd., Cambridge, United Kingdom.
  • Brewis N; F-star Therapeutics Ltd., Cambridge, United Kingdom.
Clin Cancer Res ; 26(15): 4154-4167, 2020 08 01.
Article in En | MEDLINE | ID: mdl-32345647
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Antibodies, Bispecific / Tumor Necrosis Factor Receptor Superfamily, Member 9 / B7-H1 Antigen / Antineoplastic Agents, Immunological Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2020 Document type: Article Affiliation country: United kingdom Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Antibodies, Bispecific / Tumor Necrosis Factor Receptor Superfamily, Member 9 / B7-H1 Antigen / Antineoplastic Agents, Immunological Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2020 Document type: Article Affiliation country: United kingdom Country of publication: United States